AAV with mIP2 promoter driven ECFP

This AAV expresses ECFP driven by an islet mIP2 promoter.

This promoter is based on the 1.1 Kb regulatory region of mouse pre-proinsulin II gene, also known as ins2, ins-2, ins-II, insulin-II, or Mody4. It is commonly used for beta cell-specific gene expression in the pancreatic islet. (m)INS2 promoter is also referred as the mIP2 or mIP2 promoter.

Enhanced Cyan fluorescence protein(ECFP) is a cyan variant from the Aequorea GFP, with a Excitation/Emission spectrum around 434nm/477nm. Other versions of fluorescent proteins with similar excitation and emission spectrums include mcerulean3, mTurquoise, and SCFP