AAV with GFAP(2.2) promoter driven EGFP
Cat. No: VB4924
Availability:
Immediate
Name:
AAV-GFAP(2.2)-EGFP-WPRE
This AAV expresses EGFP driven by an astrocyte GFAP(2.2) promoter.
The GFAP(2.2) promoter is based on human glial fibrillary acidic protein gene (GFAP), which is the major intermediate filament protein in astrocytes. It has been shown that approximately 2 kb of 5'-flanking DNA of the human GFAP gene is sufficient to direct transgene expression to astrocytes and confer developmental/injury-induced regulation.
EGFP is derived from the Aequorea GFP with a Excitation/Emission spectrum around 488nm/507nm. It is the most commonly used imaging probe. Other fluorescent proteins with similar emission spectrums are Emerald, and T-Sapphire
The GFAP(2.2) promoter is based on human glial fibrillary acidic protein gene (GFAP), which is the major intermediate filament protein in astrocytes. It has been shown that approximately 2 kb of 5'-flanking DNA of the human GFAP gene is sufficient to direct transgene expression to astrocytes and confer developmental/injury-induced regulation.
EGFP is derived from the Aequorea GFP with a Excitation/Emission spectrum around 488nm/507nm. It is the most commonly used imaging probe. Other fluorescent proteins with similar emission spectrums are Emerald, and T-Sapphire
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- GFAP(2.2) (astrocyte)
- Storage Buffer
- PBS/5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^13 GC/ml
Product Citations
This product is referenced in the following publications:
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
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