AAV with ALB(1.7) promoter driven EYFP

This AAV expresses EYFP driven by a liver ALB(1.7) promoter.

The ALB(1.7) is a shorter version of the ALB(1.9) promoter with a total length of 1.7 Kb. In mouse liver cells, the transgene expression from this ALB(1.7) synthetic promoter is about 3-5 times lower than that of the ALB(1.9) promoter but 20-200 fold greater than that of the CMV promoter 10-20 weeks after plasmid injection into mouse liver.

YFP is the longest wavelength-emitting variants of Aequorea GFP. The enhanced version, EYFP, has become one of the brightest and most widely utilized of the fluorescent proteins with an Excitation/Emission spectrum centered around 514nm/527nm. Other fluorescent proteins with similar emission spectrums include Topaz, Venus, Citrine and mCitrine