AAV with ALB(1.7) promoter driven EBFP2

This AAV expresses EBFP2 driven by a liver ALB(1.7) promoter.

The ALB(1.7) is a shorter version of the ALB(1.9) promoter with a total length of 1.7 Kb. In mouse liver cells, the transgene expression from this ALB(1.7) synthetic promoter is about 3-5 times lower than that of the ALB(1.9) promoter but 20-200 fold greater than that of the CMV promoter 10-20 weeks after plasmid injection into mouse liver.

EBFP2 is new version of blue fluorescent protein (BFP), with an Excitation/Emission spectrum of 380nm/448nm. EBFP2 is the brightest and most photo-stable of the BFPs; it is useful for situations in which a blue probe is required, especially when two-photon excitation is used