AAV with GFAP(2.2) promoter driven Venus
Cat. No: VB1176
Availability:
2-3 weeks
Name:
AAV-GFAP(2.2)-Venus
This AAV expresses Venus driven by an astrocyte GFAP(2.2) promoter.
The GFAP(2.2) promoter is based on human glial fibrillary acidic protein gene (GFAP), which is the major intermediate filament protein in astrocytes. It has been shown that approximately 2 kb of 5'-flanking DNA of the human GFAP gene is sufficient to direct transgene expression to astrocytes and confer developmental/injury-induced regulation.
Like mCitrine and EYFP, Venus was developed in an effort to get better variants of YFP in terms of brightness and photo-stability. Venus has an Excitation/Emission spectrum of 515nm/529nm which is almost identical to that of EYFP and mCitrine.
The GFAP(2.2) promoter is based on human glial fibrillary acidic protein gene (GFAP), which is the major intermediate filament protein in astrocytes. It has been shown that approximately 2 kb of 5'-flanking DNA of the human GFAP gene is sufficient to direct transgene expression to astrocytes and confer developmental/injury-induced regulation.
Like mCitrine and EYFP, Venus was developed in an effort to get better variants of YFP in terms of brightness and photo-stability. Venus has an Excitation/Emission spectrum of 515nm/529nm which is almost identical to that of EYFP and mCitrine.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- GFAP(2.2) (astrocyte)
- Storage Buffer
- PBS/5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^13 GC/ml
Vector Biolabs
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