mouse SRRT shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-281128
Availability:
3-5 weeks
Name:
Ad-m-SRRT-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Srrt.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Srrt
- Gene Name
- serrate RNA effector molecule homolog (Arabidopsis)
- Gene ID
- 83701
- Gene Synonyms
- 2810019G02Rik; Ars2; Asr2; ASR2A; ASR2B; ASR2C; ASR2D
- ORF Size
- 2607 bp
- RefSeq#
- NM_031405
- Gene Description
- Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
- UniGene ID
- Mm.387734
Related Products
Product | Cat No. |
---|---|
AAV-h-SRRT | AAV-224368 |
AAV-m-SRRT | AAV-281128 |
Ad-h-SRRT | ADV-224368 |
Ad-m-SRRT | ADV-281128 |
AAV-h-SRRT-shRNA | shAAV-224368 |
AAV-m-SRRT-shRNA | shAAV-281128 |
Ad-h-SRRT-shRNA | shADV-224368 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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