mouse NDFIP2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ndfip2

Gene Name

Nedd4 family interacting protein 2

Gene ID

76273

Gene Synonyms

0710001O20Rik; 2810436B12Rik; 9130207N19Rik; mKIAA1165; N4wbp5a

ORF Size

726 bp

RefSeq#

NM_029561

Gene Description

Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.

UniGene ID

Mm.290669