mouse ZBP1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-276503
Availability:
5-8 weeks
Name:
Ad-m-ZBP1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Zbp1.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Zbp1
- Gene Name
- Z-DNA binding protein 1
- Gene ID
- 58203
- Gene Synonyms
- 2010010H03Rik; Dai; Dlm1; mZaDLM
- ORF Size
- 1236 bp
- RefSeq#
- NM_021394
- Gene Description
- Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
- UniGene ID
- Mm.116687
Related Products
Product | Cat No. |
---|---|
AAV-h-ZBP1 | AAV-228040 |
AAV-m-ZBP1 | AAV-276503 |
Ad-h-ZBP1 | ADV-228040 |
Ad-m-ZBP1 | ADV-276503 |
AAV-h-ZBP1-shRNA | shAAV-228040 |
AAV-m-ZBP1-shRNA | shAAV-276503 |
Ad-h-ZBP1-shRNA | shADV-228040 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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