mouse UNC13D shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-275633
Availability:
3-5 weeks
Name:
Ad-m-UNC13D-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Unc13d.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Unc13d
- Gene Name
- unc-13 homolog D (C. elegans)
- Gene ID
- 70450
- Gene Synonyms
- 2610108D09Rik; Jinx; mFLJ00067; Munc13-4
- ORF Size
- 3252 bp
- RefSeq#
- NM_001009573
- Gene Description
- Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
- UniGene ID
- Mm.259460
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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