mouse UCHL1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Uchl1

Gene Name

ubiquitin carboxy-terminal hydrolase L1

Gene ID

22223

Gene Synonyms

AW822034; C88048; gad; PGP 9.5; PGP9.5; R75593; UCH-L1; UCHL-1

ORF Size

672 bp

RefSeq#

NM_011670

Gene Description

Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

UniGene ID

Mm.29807