mouse TNF shRNA silencing Adenovirus

Cat. No: shADV-274675

Availability: 5-8 weeks

Name: Ad-m-TNF-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Tnf.

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Species: Mouse
Gene Symbol: Tnf
Gene Name: tumor necrosis factor
Gene ID: 21926
Gene Synonyms: DIF; TNF-a; TNF-alpha; Tnfa; TNFalpha; Tnfsf1a; TNFSF2; Tnlg1f
ORF Size: 708 bp
RefSeq#: NM_013693
Gene Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation|Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
UniGene ID: Mm.1293