mouse TAX1BP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Tax1bp1

Gene Name

Tax1 (human T cell leukemia virus type I) binding protein 1

Gene ID

52440

Gene Synonyms

1200003J11Rik; 1700069J21Rik; AA930106; D6Ertd404e; D6Ertd772e; T6bp; TXBP151

ORF Size

2445 bp

RefSeq#

NM_025816

Gene Description

Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.

UniGene ID

Mm.389757