mouse SPC25 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Spc25

Gene Name

SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)

Gene ID

66442

Gene Synonyms

2600017H08Rik; 2610205L13Rik; Spbc25

ORF Size

681 bp

RefSeq#

NM_025565

Gene Description

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.

UniGene ID

Mm.272969