mouse SORBS2 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Sorbs2

Gene Name

sorbin and SH3 domain containing 2

Gene ID

234214

Gene Synonyms

2010203O03Rik; 9430041O17Rik; A530071H08; Argbp2; mKIAA0777; nArgBP2

ORF Size

3819 bp

RefSeq#

NM_172752

Gene Description

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

UniGene ID

Mm.447653