mouse SARM1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-271364
Availability:
5-8 weeks
Name:
Ad-m-SARM1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Sarm1.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Sarm1
- Gene Name
- sterile alpha and HEAT/Armadillo motif containing 1
- Gene ID
- 237868
- Gene Synonyms
- A830091I15Rik; C78606; MyD885; Sarm
- ORF Size
- 2175 bp
- RefSeq#
- NM_172795
- Gene Description
- Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
- UniGene ID
- Mm.210332
Related Products
Product | Cat No. |
---|---|
AAV-m-SARM1 | AAV-271364 |
Ad-m-SARM1 | ADV-271364 |
AAV-m-SARM1-shRNA | shAAV-271364 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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