mouse RPE65 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-270828
Availability:
5-8 weeks
Name:
Ad-m-RPE65-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Rpe65.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Rpe65
- Gene Name
- retinal pigment epithelium 65
- Gene ID
- 19892
- Gene Synonyms
- 65kDa; A930029L06Rik; LCA2; Mord1; rd12; RP20
- ORF Size
- 1602 bp
- RefSeq#
- NM_029987
- Gene Description
- Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
- UniGene ID
- Mm.131708
Related Products
Product | Cat No. |
---|---|
AAV-h-RPE65 | AAV-221550 |
AAV-m-RPE65 | AAV-270828 |
Ad-h-RPE65 | ADV-221550 |
Ad-m-RPE65 | ADV-270828 |
AAV-h-RPE65-shRNA | shAAV-221550 |
AAV-m-RPE65-shRNA | shAAV-270828 |
Ad-h-RPE65-shRNA | shADV-221550 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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