mouse RAPGEF4 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Rapgef4

Gene Name

Rap guanine nucleotide exchange factor (GEF) 4

Gene ID

56508

Gene Synonyms

1300003D15Rik; 5730402K07Rik; 6330581N18Rik; EPAC 2; Epac-2; Epac2; mKIAA4040

ORF Size

3036 bp

RefSeq#

NM_019688

Gene Description

Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).

UniGene ID

Mm.196153