mouse PPARG shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Pparg

Gene Name

peroxisome proliferator activated receptor gamma

Gene ID

19016

Gene Synonyms

Nr1c3; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2

ORF Size

1518 bp

RefSeq#

NM_011146

Gene Description

Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.

UniGene ID

Mm.3020