mouse P2RX7 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

P2rx7

Gene Name

purinergic receptor P2X, ligand-gated ion channel, 7

Gene ID

18439

Gene Synonyms

AI467586; P2X(7); P2X7R

ORF Size

1788 bp

RefSeq#

NM_011027

Gene Description

Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

UniGene ID

Mm.42026