mouse NME3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Nme3

Gene Name

NME/NM23 nucleoside diphosphate kinase 3

Gene ID

79059

Gene Synonyms

1810009F08Rik; AI413736; DR-nm23; Ndk3; Nm23-DR; Nm23-M3

ORF Size

510 bp

RefSeq#

NM_019730

Gene Description

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.

UniGene ID

Mm.430765