mouse NDST1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-265553
Availability:
3-5 weeks
Name:
Ad-m-NDST1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Ndst1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ndst1
- Gene Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
- Gene ID
- 15531
- Gene Synonyms
- 1200015G06Rik; b2b2230Clo; Hsst; NDST-1
- ORF Size
- 2649 bp
- RefSeq#
- NM_008306
- Gene Description
- Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
- UniGene ID
- Mm.181862
Related Products
Product | Cat No. |
---|---|
AAV-h-NDST1 | AAV-216463 |
AAV-m-NDST1 | AAV-265553 |
Ad-h-NDST1 | ADV-216463 |
Ad-m-NDST1 | ADV-265553 |
AAV-h-NDST1-shRNA | shAAV-216463 |
AAV-m-NDST1-shRNA | shAAV-265553 |
Ad-h-NDST1-shRNA | shADV-216463 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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