mouse MUL1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-265196
Availability:
Immediate
Name:
Ad-m-MUL1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Mul1.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Mul1
- Gene Name
- mitochondrial ubiquitin ligase activator of NFKB 1
- Gene ID
- 68350
- Gene Synonyms
- 0610009K11Rik; AV000801; Gide
- ORF Size
- 1059 bp
- RefSeq#
- NM_026689
- Gene Description
- Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- UniGene ID
- Mm.103413
Related Products
Product | Cat No. |
---|---|
AAV-h-MUL1 | AAV-216078 |
AAV-m-MUL1 | AAV-265196 |
Ad-h-MUL1 | ADV-216078 |
Ad-m-MUL1 | ADV-265196 |
AAV-h-MUL1-shRNA | shAAV-216078 |
AAV-m-MUL1-shRNA | shAAV-265196 |
Ad-h-MUL1-shRNA | shADV-216078 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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