mouse MFN1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Mfn1

Gene Name

mitofusin 1

Gene ID

67414

Gene Synonyms

2310002F04Rik; 6330416C07Rik; D3Ertd265e; HR2; mKIAA4032

ORF Size

2226 bp

RefSeq#

NM_024200

Gene Description

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

UniGene ID

Mm.477166