mouse LRRFIP2 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Lrrfip2

Gene Name

leucine rich repeat (in FLII) interacting protein 2

Gene ID

71268

Gene Synonyms

5133400F20Rik; AI850587

ORF Size

1248 bp

RefSeq#

NM_027742

Gene Description

LRRFIP2 may function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

UniGene ID

Mm.302287