mouse ITGA7 shRNA silencing Adenovirus

Cat. No: shADV-262435

Availability: 5-8 weeks

Name: Ad-m-ITGA7-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Itga7.

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Species: Mouse
Gene Symbol: Itga7
Gene Name: integrin alpha 7
Gene ID: 16404
Gene Synonyms: alpha7; [a]7
ORF Size: 3408 bp
RefSeq#: NM_008398
Gene Description: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
UniGene ID: Mm.179747