mouse IRF8 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Irf8

Gene Name

interferon regulatory factor 8

Gene ID

15900

Gene Synonyms

AI893568; ICSBP; Icsbp1; IRF-8; Myls

ORF Size

1275 bp

RefSeq#

NM_008320

Gene Description

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system.

UniGene ID

Mm.334861