mouse GPBAR1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Gpbar1

Gene Name

G protein-coupled bile acid receptor 1

Gene ID

227289

Gene Synonyms

BG37; GPCR; GPR131; M-BAR; TGR5

ORF Size

990 bp

RefSeq#

NM_174985

Gene Description

Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

UniGene ID

Mm.246587