mouse GOPC shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Gopc

Gene Name

golgi associated PDZ and coiled-coil motif containing

Gene ID

94221

Gene Synonyms

2210402P09Rik; AI844555; CAL; FIG; GOPC1; PIST

ORF Size

1368 bp

RefSeq#

NM_053187

Gene Description

Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.

UniGene ID

Mm.390258