mouse GNPTAB shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Gnptab

Gene Name

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

Gene ID

432486

Gene Synonyms

EG432486; mKIAA1208

ORF Size

2766 bp

RefSeq#

NM_001004164

Gene Description

Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.

UniGene ID

Mm.335190