mouse GADD45GIP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Gadd45gip1

Gene Name

growth arrest and DNA-damage-inducible, gamma interacting protein 1

Gene ID

102060

Gene Synonyms

2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1

ORF Size

669 bp

RefSeq#

NM_183358

Gene Description

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.

UniGene ID

Mm.255539