mouse FNBP1L shRNA silencing Adenovirus

Cat. No: shADV-259521

Availability: 5-8 weeks

Name: Ad-m-FNBP1L-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Fnbp1l.

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Species: Mouse
Gene Symbol: Fnbp1l
Gene Name: formin binding protein 1-like
Gene ID: 214459
Gene Synonyms: 2610318I01Rik; AW548221; toca-1; TOCA1
ORF Size: 1116 bp
RefSeq#: NM_153118
Gene Description: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens.
UniGene ID: Mm.470230