mouse FBXL3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Fbxl3

Gene Name

F-box and leucine-rich repeat protein 3

Gene ID

50789

Gene Synonyms

AU041772; AW212966; FBK; Fbl3a; Fbxl3a; Ovtm; Play68

ORF Size

1287 bp

RefSeq#

NM_015822

Gene Description

Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

UniGene ID

Mm.214746