mouse FANCM shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Fancm

Gene Name

Fanconi anemia, complementation group M

Gene ID

104806

Gene Synonyms

AI427100; C730036B14Rik; D12Ertd364e

ORF Size

6066 bp

RefSeq#

NM_178912

Gene Description

ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.

UniGene ID

Mm.374847