mouse ERCC3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ercc3

Gene Name

excision repair cross-complementing rodent repair deficiency, complementation group 3

Gene ID

13872

Gene Synonyms

BTF2 p89; Ercc-3; XPB

ORF Size

2352 bp

RefSeq#

NM_133658

Gene Description

ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.

UniGene ID

Mm.282335