mouse ASCC3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

ASCC3

Gene Name

activating signal cointegrator 1 complex subunit 3

Gene ID

77987

Gene Synonyms

ASC1p200; B630009I04Rik; BC023451; D430001L07Rik; D630041L21; Helic1; RNAH;

ORF Size

3387 bp

RefSeq#

NM_198007

Gene Description

3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.

UniGene ID

Mm.222497