mouse CLNS1A shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Clns1a

Gene Name

chloride channel, nucleotide-sensitive, 1A

Gene ID

12729

Gene Synonyms

2610036D06Rik; 2610100O04Rik; Clci; Clcni; ICLN

ORF Size

726 bp

RefSeq#

NM_023671

Gene Description

The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.

UniGene ID

Mm.21482