mouse CHORDC1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Chordc1

Gene Name

cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1

Gene ID

66917

Gene Synonyms

1110001O09Rik; AA409036; Chp-1; morgana

ORF Size

996 bp

RefSeq#

NM_025844

Gene Description

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.

UniGene ID

Mm.476826