mouse CFB shRNA silencing Adenovirus

Cat. No: shADV-255325

Availability: 5-8 weeks

Name: Ad-m-CFB-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Cfb.

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Species: Mouse
Gene Symbol: Cfb
Gene Name: complement factor B
Gene ID: 14962
Gene Synonyms: AI195813; AI255840; B; Bf; C2; Fb; H2-Bf
ORF Size: 2286 bp
RefSeq#: NM_008198
Gene Description: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
UniGene ID: Mm.653