mouse BRIP1 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Brip1

Gene Name

BRCA1 interacting protein C-terminal helicase 1

Gene ID

237911

Gene Synonyms

3110009N10Rik; 8030460J03Rik; Bach1; FACJ; Fancj; OF

ORF Size

3525 bp

RefSeq#

NM_178309

Gene Description

DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

UniGene ID

Mm.186143