mouse ATP6AP2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Atp6ap2

Gene Name

ATPase, H+ transporting, lysosomal accessory protein 2

Gene ID

70495

Gene Synonyms

(P)RR; 5730403E06Rik; APT6M8-9; Atp6ip2; ATP6M8-9; M8-9; PRR

ORF Size

1053 bp

RefSeq#

NM_027439

Gene Description

Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).

UniGene ID

Mm.25148