mouse ABCC1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Abcc1

Gene Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Gene ID

17250

Gene Synonyms

Abcc1a; Abcc1b; Mdrap; MRP; Mrp1

ORF Size

4587 bp

RefSeq#

NM_008576

Gene Description

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

UniGene ID

Mm.196634