mouse AADAC shRNA silencing Adenovirus

Cat. No: shADV-251727

Availability: 5-8 weeks

Name: Ad-m-AADAC-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Aadac.

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Species: Mouse
Gene Symbol: Aadac
Gene Name: arylacetamide deacetylase (esterase)
Gene ID: 67758
Gene Synonyms: 5033417E09Rik; Aada; AI265437
ORF Size: 1197 bp
RefSeq#: NM_023383
Gene Description: Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
UniGene ID: Mm.24547