human IRS1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IRS1

Gene Name

insulin receptor substrate 1

Gene ID

3667

Gene Synonyms

HIRS-1

ORF Size

3729 bp

RefSeq#

NM_005544

Gene Description

IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

UniGene ID

Hs.471508

HGNC ID

HGNC:6125