human VPS25 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

VPS25

Gene Name

vacuolar protein sorting 25 homolog

Gene ID

84313

Gene Synonyms

DERP9; EAP20; FAP20

ORF Size

531 bp

RefSeq#

NM_032353

Gene Description

VPS25, VPS36 (MIM 610903), and SNF8 (MIM 610904) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS25, VPS36, and SNF8 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 (PubMed 15755741); Kamura et al., 2001 (PubMed 11278625)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.500165

HGNC ID

HGNC:28122