human UHRF2 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-227166
Availability:
5-8 weeks
Name:
Ad-h-UHRF2-shRNA
This is an Adenovirus expressing shRNA for silencing of Human UHRF2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UHRF2
- Gene Name
- ubiquitin like with PHD and ring finger domains 2
- Gene ID
- 115426
- Gene Synonyms
- NIRF; RNF107; TDRD23; URF2
- ORF Size
- 1512 bp
- RefSeq#
- NM_152896
- Gene Description
- UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
- UniGene ID
- Hs.493401
- HGNC ID
- HGNC:12557
Related Products
Product | Cat No. |
---|---|
AAV-h-UHRF2 | AAV-227166 |
AAV-m-UHRF2 | AAV-275613 |
Ad-h-UHRF2 | ADV-227166 |
Ad-m-UHRF2 | ADV-275613 |
AAV-h-UHRF2-shRNA | shAAV-227166 |
AAV-m-UHRF2-shRNA | shAAV-275613 |
Ad-m-UHRF2-shRNA | shADV-275613 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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