human UBA6 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

UBA6

Gene Name

ubiquitin like modifier activating enzyme 6

Gene ID

55236

Gene Synonyms

E1-L2; MOP-4; UBE1L2

ORF Size

3159 bp

RefSeq#

NM_018227

Gene Description

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 (PubMed 17597759)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.212774

HGNC ID

HGNC:25581