human TYW1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TYW1

Gene Name

tRNA-yW synthesizing protein 1 homolog

Gene ID

55253

Gene Synonyms

RSAFD1; TYW1A; YPL207W

ORF Size

1155 bp

RefSeq#

NM_018264

Gene Description

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.520917

HGNC ID

HGNC:25598