human TRAM1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TRAM1

Gene Name

translocation associated membrane protein 1

Gene ID

23471

Gene Synonyms

PNAS8; TRAM; TRAMP

ORF Size

1125 bp

RefSeq#

NM_014294

Gene Description

TRAM1 encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause.

UniGene ID

Hs.491988

HGNC ID

HGNC:20568