human TLR2 shRNA silencing Adenovirus

Cat. No: shADV-225587

Availability: 5-8 weeks

Name: Ad-h-TLR2-shRNA

This is an Adenovirus expressing shRNA for silencing of Human TLR2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Species: Human
Gene Symbol: TLR2
Gene Name: toll like receptor 2
Gene ID: 7097
Gene Synonyms: CD282; TIL4
ORF Size: 2355 bp
RefSeq#: NM_003264
Gene Description: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
UniGene ID: Hs.519033
HGNC ID: HGNC:11848