human TBC1D24 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TBC1D24

Gene Name

TBC1 domain family member 24

Gene ID

57465

Gene Synonyms

DFNA65; DFNB86; DOORS; EIEE16; FIME; TLDC6

ORF Size

1680 bp

RefSeq#

NM_020705

Gene Description

TBC1D24 encodes a protein with a conserved domain, referred to as the TBC domain, characteristic of proteins which interact with GTPases. TBC domain proteins may serve as GTPase-activating proteins for a particular group of GTPases, the Rab (Ras-related proteins in brain) small GTPases which are involved in the regulation of membrane trafficking. Mutations in this gene are associated with familial infantile myoclonic epilepsy. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.353087

HGNC ID

HGNC:29203